empPvalues.Rd
Andersen et al. (2003) used a fixed \(Chi^2\) threshold of 0.05 to identify organelle-specific candidates. This function computes empirical p-values by permutation the markers relative intensities and computed null \(Chi^2\) values.
empPvalues(marker, corMatrix, n = 100, ...)
A numerics
with markers relative intensities.
A matrix
of nrow(corMatrix)
protein relative
intensities to be compares against the marker.
The number of iterations.
Additional parameters to be passed to chi2
.
A numeric
of length nrow(corMatrix)
.
chi2
for \(Chi^2\) calculation.
Andersen, J. S., Wilkinson, C. J., Mayor, T., Mortensen, P. et al., Proteomic characterization of the human centrosome by protein correlation profiling. Nature 2003, 426, 570 - 574.